Complete story — includes the ending
Reese and Finch become trapped in a hospital manipulated electronically by Samaritan to have initiated an outbreak of what it said to be a combination of H5N1 (avian flu) and live human flu virus; a synthesized, super-powered strain of the flu, and send Jeff Blackwell at the hospital. It appeared as though the epidemic was overkill to eliminate three targets in the hospital. Since the Machine is an open system, Root was able to use its abilities to find and retrieve a cure, saving the lives of two hospital workers and Fusco. Shaw executes her escape plan and finds herself in a jail in Johannesburg, South Africa. While escaping, Lambert taunts her by claiming that she is actually in another simulation; she kills him, and is last seen driving in Lambert's vehicle at night at high speed, presumably to an airport. Fusco indefinitely chooses to distance himself from the team. Blackwell and his handler, Mona, discuss the quelled epidemic and declare it a success: The CDC is requiring everyone to be vaccinated, which will result in Samaritan learning everyone's DNA.
Sources and content license
Source and revision history · Adapted from Wikipedia contributors, Person of Interest season 5. HTML formatting and reference markers removed. · Content license