Charlotte, an older woman who has spent the last six months taking care of her husband Eddie, is rushed to Princeton Plainsboro for immediate treatment after collapsing from respiratory failure at Eddie's deathbed. With both in the hospital, the husband and wife team becomes a double mystery when Eddie's condition sporadically improves while Charlotte's condition deteriorates. Dr. Lawrence Kutner dies of suicide using a gun without any explanation why. While most of the cast grieve, House tries in vain to understand why Kutner died.
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Complete story — includes the ending
An older woman, Charlotte ( Colleen Camp ), who has been taking care of her husband Eddie ( Meat Loaf ) for the last six months, is rushed to Princeton-Plainsboro for treatment after collapsing at Eddie's deathbed from respiratory failure. The case is further complicated as Eddie's condition improves while Charlotte's deteriorates. Meanwhile, the team tries to deal with their grief over Kutner's sudden suicide. Final diagnosis: Visceral leishmaniasis (Charlotte) and Blastomycosis (Eddie)