Saints Row 2

Five years after the explosion on Richard Hughes' yacht, the player character (Charles Shaughnessy, Kenn Michael, Alex Mendoza, Katie Semine, G. K. Bowes, or Rebecca Sanabria), who was the sole survivor, awakens from a coma within the infirmary of Stilwater's maximum security prison after undergoing extensive plastic surgery. They escape to Stilwater with the help of Carlos Mendoza (Joe Camareno), the brother of a former 3rd Street Saints member. Carlos explains that the Saints have disbanded, with most members being arrested by Troy Bradshaw (Michael Rapaport), an undercover cop who had infiltrated the gang as a lieutenant and has since become chief of police, using his influence to protect the imprisoned Saints. In their absence, three new gangs have taken over the city: the Brotherhood, a metalhead gang who conduct gun-running operations; the Sons of Samedi, a Haitian Vodou gang who produce and sell drugs; and the Ronin, a Japanese bosozoku gang focusing on gambling and porn. Furthermore, the Saints' former base of operations, the Saint's Row district, has been redeveloped into a pristine commercial and residential area by the Ultor Corporation, which has further plans for Stilwater.
The player works to rebuild the Saints, rescuing former lieutenant Johnny Gat (Daniel Dae Kim) from his trial. The pair then recruit new members, including Carlos and Gat's acquaintances, Pierce Washington (Arif S. Kinchen) and Shaundi (Eliza Dushku), and set up a new headquarters in a hotel destroyed by an earthquake. The player steps up as the Saints' new leader, adopting the moniker of "The Boss", and declares war on the rival gangs, assigning their lieutenants – Gat, Carlos, Pierce and Shaundi – to discover more about each.
Carlos researches the Brotherhood, led by Maero (Michael Dorn). After the Boss rejects Maero's deal to join forces and split their profits (80% to the Brotherhood and 20% to the Saints), a series of rebound retaliations result in the deaths of Carlos, who is dragged by a speeding truck and mercy killed by the Boss, and Maero's girlfriend Jessica (Jaime Pressly), whom the Boss locks in her car to be inadvertently crushed by Maero with his monster truck. After assaulting the Brotherhood's headquarters and forcing Maero to flee, the Boss kills him during a demolition derby to end the Brotherhood.
Shaundi investigates the Sons of Samedi, led by "The General" (Greg Eagles) and his right-hand man, Mr. Sunshine (Phil LaMarr). After the Saints disrupt the Samedi's operations and steal most of their customers, Samedi lieutenant and one of Shaundi's exes, DJ Veteran Child (Neil Patrick Harris), is forced by the gang to kidnap Shaundi. The Boss kills Veteran Child to rescue Shaundi and continues their attacks against the Samedi, destroying their drug factories and killing Mr. Sunshine. After hacking into the city's camera system to track down the General's armored limousine, which doubles as his headquarters, the Saints set up an ambush and kill the General, ending the Sons of Samedi.
Pierce and Gat focus on the Ronin, led by Shogo Akuji (Yuri Lowenthal) and his second-in-command, Jyunichi (Brian Tee), on behalf of Shogo's father, Kazuo, who leads international operations. After the Saints rob their casino, the Ronin retaliate by infiltrating the home of Gat's girlfriend Aisha (Sy Smith), killing her and severely wounding Gat. After protecting Gat from an assassination attempt while hospitalized, the Boss finds and kills Jyunichi, who was betrayed by Shogo out of envy for Jyunichi's closer bond with Kazuo. Once Gat recovers, he and the Boss eliminate the Ronin's remaining members, burying Shogo alive when he disrupts Aisha's funeral, and eventually killing Kazuo himself.
After defeating the rival gangs, the Saints find themselves targeted by Ultor's power-hungry CEO, Dane Vogel (Jay Mohr), who was playing the gangs against each other to lower real estate prices throughout Stilwater and allow Ultor to purchase and redevelop the land. After fending off several attacks by Ultor's private security forces, the Saints retaliate by destroying one of the company's labs and killing its board of directors. Taking advantage of the situation to assume full control of Ultor, Vogel decides to personally deal with the Saints, but is ambushed by the Boss at a press conference. The Boss fights their way to Vogel's office and kills him, allowing the Saints to rule over Stilwater undisputed.
At any point during the game, the Boss can listen to wiretap conversations at the police station, which reveal that former Saints leader Julius Little (Keith David) had disbanded the gang at Troy's request and planted the bomb on Hughes' yacht to kill the player, knowing they would oppose his decision. Upon discovering the truth, the Boss calls former Saints lieutenant Dexter "Dex" Jackson, who left the gang to work for Ultor, and arranges a meeting at the Saints' old church to discuss their findings. Once there, however, the Boss is met by Julius instead, and the pair are attacked by Ultor security forces sent by Dex. After escaping the ambush, the Boss shoots Julius, who defends his actions and accuses the Boss of straying away from the Saints' ideals. Unmoved, the Boss finishes Julius off.