Resident Evil 3

On September 28, 1998, 24 hours prior to the events of Resident Evil 2, most of Raccoon City's citizens have turned into zombies as the result of an outbreak of the T-virus, a mutagenic virus secretly developed by the pharmaceutical company Umbrella. Jill Valentine, former member of the Raccoon Police Department's Special Tactics And Rescue Service (S.T.A.R.S.), is attacked in her apartment by an intelligent bioweapon known as the Nemesis T-Type, specifically programmed by Umbrella to eliminate all surviving S.T.A.R.S. members. Briefly joined by fellow S.T.A.R.S. officer Brad Vickers before he is killed by zombies, Jill evades Nemesis and is rescued by Umbrella Biohazard Countermeasure Service (U.B.C.S.) mercenary Carlos Oliveira. Carlos explains that he and his group of surviving U.B.C.S. mercenaries - Mikhail Victor, Tyrell Patrick, and Nicholai Ginovaef - have set up subway trains to evacuate civilians from the city. Jill helps them reactivate power to the subway and departs on a train with Nicholai and Mikhail, while Carlos and Tyrell remain behind to find Dr. Nathaniel Bard, an Umbrella scientist who may have developed a vaccine for the T-virus.
After Mikhail expresses his suspicions toward Nicholai over how their platoon was ambushed by zombies, Nemesis attacks the train and kills the civilians. Nicholai betrays and locks Jill and Mikhail out, and the latter sacrifices himself by detonating an explosive that derails the train. Meanwhile, reaching the police department on the notion that Bard is at the S.T.A.R.S. office, Carlos and Tyrell learn the scientist took refuge at a nearby hospital. Carlos is contacted by Jill, who survived the crash while being pursued by a mutating Nemesis. She manages to escape and defeat Nemesis, but loses consciousness after the monster infects her with the T-virus. Carlos finds Jill half a day later and takes her to the hospital, hoping to find a cure. There, he also learns that Bard was murdered, and a video entry from the scientist reveals that Umbrella's board is wiping out the vaccines and any evidence connecting the company to the T-Virus. After Carlos retrieves Bard's vaccine and administers it to Jill, Tyrell discovers that the U.S. government plans to destroy Raccoon City in a missile strike to eradicate the T-virus infestation. Carlos travels to a lab underneath the hospital to find more vaccines, while Tyrell tries to contact whomever he can to prevent the missile strike.
Jill wakes on the day of the missile strike, October 1, and follows Carlos to the lab. Tyrell informs her that the U.S. government will not launch the missiles if they can retrieve a vaccine from the lab within a few hours. Although Nemesis kills Tyrell shortly afterward, Jill manages to synthesize a vaccine. She also learns that Nicholai is a supervisor hired by an unknown contractor to sabotage Umbrella's efforts to hide their involvement while collecting combat data on the company's bioweapons, including Nemesis. An encounter with Nemesis prompts Nicholai to retrieve the vaccine from Jill as he leaves her to fight the monster. Jill eliminates Nemesis with a railgun and confronts Nicholai on a helipad. Nicholai destroys the vaccine, acknowledging that the city's fate is not important as long as he gets paid for sabotaging Umbrella. Carlos intervenes and restrains Nicholai, prompting Jill to shoot and injure the man. Disgusted by his greed, Jill escapes the city with Carlos via helicopter, leaving Nicholai behind. As the city is destroyed by the missile strike, Jill vows to take down Umbrella at all costs.