Resident Evil 3: Nemesis

On September 28, 1998, 24 hours prior to the events of Resident Evil 2, former Special Tactics And Rescue Service (S.T.A.R.S.) member Jill Valentine attempts to escape from Raccoon City. Most of the population has been transformed into zombies by an outbreak of the T-virus, the gruesome biological weapon secretly developed by the pharmaceutical company Umbrella Corporation. After fighting through zombies and mutants on her way to the Raccoon City Police Department, Jill runs into fellow team member Brad Vickers, who is later killed by a new enemy. This creature, Nemesis-T Type, is a bio-organic weapon programmed to target the surviving S.T.A.R.S. members, who had knowledge of Umbrella's experiments. After she evades Nemesis, Jill encounters three surviving members of the Umbrella Biohazard Countermeasure Service (U.B.C.S.): Carlos Oliveira, Mikhail Victor, and Nikolai Zinoviev. Nikolai explains to Jill that a rescue helicopter can be contacted if they manage to reach the city's Clock Tower to ring the bell.
When they are finished repairing a cable car, Nikolai goes missing and is presumed dead. Nemesis then corners the remaining members of the group onto the car as they head to the tower. Mikhail sacrifices himself with a grenade, causing the car to crash into the tower's central courtyard and separating Jill and Carlos briefly. At the Clock Tower, Jill summons the helicopter by ringing the Clock Tower's bell before being confronted by Nemesis, which destroys the helicopter and infects Jill with the T-virus. Jill manages to temporarily defeat Nemesis but she falls unconscious due to the T-virus infection given by Nemesis. Carlos finds Jill and takes her to safety within the Clock Tower. Three days later, he finds a vaccine for Jill's T-virus infection in a nearby Umbrella owned hospital, then returns and administers it to her, saving her.
After she regains consciousness on the morning of October 1, 1998, Jill proceeds towards the Raccoon Park to search for an escape route and enters the park caretaker's cabin. There, she runs into Nikolai, who reveals that he is a "supervisor" sent into Raccoon City to gather combat data on Umbrella's bioweapons. Nikolai retreats, and Jill later is confronted by the Gravedigger, a massive worm-like creature. Jill defeats it and escapes to an abandoned Umbrella factory at the edge of town through the worm’s tunnels. Inside the factory, Jill meets up with Carlos, who tells her that the U.S. government is planning to launch an experimental thermobaric missile into Raccoon City to eradicate the T-virus infestation. After confronting Nemesis and grabbing a keycard needed to escape, Jill learns that the missile attack on Raccoon City has begun, with only a short time left before the city is destroyed.
Depending on the path taken by the player, Jill's final encounter with Nikolai will differ. In one version of the events, Nikolai will attempt to start a gunfight with Jill, only to be ambushed and killed by Nemesis. In another event, Nikolai will hijack Jill's intended escape chopper, and the player must either reason with Nikolai or destroy the helicopter. If Jill negotiates with Nikolai, he reveals that he has killed the other supervisors and boasts about collecting the bounty placed on Jill by Umbrella before escaping. Regardless of Nikolai's fate, Jill makes her way to the rear yard and confronts Nemesis again. After an intense battle, Jill defeats Nemesis with the help of a large prototype railgun before meeting up with Carlos and escaping the city via a helicopter. If the previous escape chopper was stolen by Nikolai, Jill and Carlos will instead meet up with S.T.A.R.S. Alpha Team's weapons specialist Barry Burton, who helps them escape in his helicopter. At sunrise, the missile vaporizes Raccoon City, and Jill swears revenge on Umbrella. A newscast then briefly details the destruction and offers condolences for the lost lives.