A Plague Tale Duology

A Plague Tale: Innocence

In November 1348, Amicia de Rune is a 15-year-old French noble living in Aquitaine during the Hundred Years' War between England and France. Her five-year-old brother, Hugo, has been ill since birth; their mother, Beatrice, an alchemist, has sheltered him in their estate while trying to devise a cure. While hunting with her father Robert in the forest, Amicia encounters an unusual substance on the ground, and her dog Lion is gruesomely consumed by an unseen entity. French Inquisition troops, led by Lord Nicholas, arrive at the de Rune estate in search of Hugo, executing Robert and slaughtering the family servants. Beatrice helps her children escape and instructs Amicia to take Hugo to a doctor named Laurentius, and is then seemingly killed.
Wanted by the Inquisition, the children find the local village and monastery overrun with hordes of rats spreading black plague. They eventually reach Laurentius's farm and find him severely ill with the plague. Laurentius implores Amicia to finish her mother's work seconds before the farm is overrun by rats; the siblings flee with Laurentius's apprentice, Lucas, to seek the Chateau d'Ombrage, which once belonged to the de Rune family. As they cross a battlefield patrolled by English soldiers, Lucas explains that Hugo's blood carries a supernatural evil called the Prima Macula, which has lain dormant within certain noble bloodlines since the Plague of Justinian. Beatrice and Laurentius had been trying to find an elixir that would mitigate Hugo's symptoms, while Vitalis Benevent, the Grand Inquisitor of France, seeks to harness Hugo's power so that the Inquisition can rule France. Hugo and Amicia are briefly captured by the English but escape with the help of sibling thieves Mélie and Arthur; Arthur is captured as the others escape to Chateau d'Ombrage.
Lucas needs a forbidden book called the Sanguinis Itinera to complete the elixir. Amicia retrieves the book with the help of a young blacksmith named Rodric, while Mélie rescues her brother. Back at the Chateau, Arthur reveals that Beatrice is still alive but imprisoned. Amicia insists they not tell Hugo, but he overhears the conversation. His anger appears to worsen his symptoms, prompting Amicia and Lucas to return to the de Rune estate and look for Beatrice's research. In a hidden laboratory, they complete the elixir and administer it to Hugo. Angry at his sister for not telling him the truth, Hugo runs away to the Inquisition in order to find Beatrice. Vitalis injects himself with Hugo's blood, but due to Lucas' elixir, he is unable to fully attain the power of the Macula.
Hugo escapes and finds Beatrice. Before their recapture, she reveals that the Macula gives him the power to control the rats. Vitalis threatens Beatrice's life to force Hugo's powers to fully awaken. Chateau d'Ombrage is then attacked by a swarm of rats guided by Hugo, still angry at Amicia. Nicholas, who is accompanying him, orders Hugo to kill Amicia, but she convinces her brother to reject the Inquisition. Nicholas kills Arthur, prompting the siblings to work together and battle Nicholas until the rats consume him. The children decide to confront Vitalis.
As they fight their way to Vitalis's cathedral, Rodric sacrifices himself to protect Hugo and Amicia. Vitalis awaits their arrival, having bred thousands of white rats that only he can control. Hugo ultimately overpowers Vitalis and Amicia kills him. Three days later, both the rats and the plague have disappeared and life begins to return to normal; many remain wary of Hugo and his power, including Mélie, who parts ways with the group. Amicia, Hugo, Lucas, and an ailing Beatrice leave in search of a new home.

A Plague Tale: Requiem

In June 1349, six months following the events of the first game, siblings Amicia (Charlotte McBurney) and Hugo de Rune (Logan Hannan), along with their mother Beatrice (Lucy Briggs-Owen) and her apprentice Lucas (Kit Connor), seek refuge among an organization of alchemists called the Order. A hostile group of survivalist beekeepers attack the siblings, causing the Prima Macula to reawaken in Hugo. The group hides in a fortified town in Provence where Beatrice enlists the aid of Order representative Vaudin (Antony Byrne) to treat Hugo; the treatments only exacerbate his condition, resulting in the town being swarmed by rats and left in ruins. Vaudin is killed while the others escape on a boat bound for the Order's headquarters in Marseille.
Unwilling to see Hugo locked up as the Order's test subject, Amicia takes Hugo and leaves Beatrice and Lucas to seek an island of which Hugo has recurring dreams, hoping it will lead to a cure for the Macula. Along the way, they are pursued by Provence soldiers, as well as mercenaries led by the disgraced knight Arnaud (Harry Myers). Arnaud offers to arrange transport to the island from Hugo's dreams, La Cuna. They sail to the island on the ship of Arnaud's smuggler friend Sophia (Anna Demetriou).
Arriving at La Cuna, the group discovers that the residents, led by Count Victor (Alistair Petrie) and Countess Emilie (Ellie Heydon), worship a pagan deity called the Child of Embers. Arnaud tries to coerce Hugo into summoning rats to attack Victor — whom he blames for the death of his son — but Amicia intervenes, and Arnaud is arrested. Amicia deduces that the Count and Countess are unknowingly worshipping a previous Macula carrier as the Child. With Sophia, they delve into an ancient Order temple, following the history of the carrier, Basilius, and his protector, Aelia. Entering a chapel where Aelia was imprisoned after rebelling against the Order, the group encounters a cult of slavers who offer human sacrifices to the Child; Hugo summons rats to kill the slavers. The group discovers that there is no cure and there never was; Basilius was imprisoned underground by the Order to contain the Macula, and Aelia died before she could reach him. Without Aelia, Basilius gave in to the Macula and unleashed the Justinian Plague. Amicia realizes the Macula showed Hugo the dream to lure him into its clutches, and they flee the prison as it collapses under a horde of rats.
Amicia and Hugo return to Victor's castle and reunite with Beatrice and Lucas. Amicia reasons that, if they are there to support Hugo, the Macula will remain dormant. However, Victor reveals Emilie believes Hugo is the Child — a myth Victor invented for Emilie, who is infertile — so they must kill Hugo's old family and adopt him. After Emilie kills Beatrice in a ritual sacrifice, Hugo summons a horde of rats which devours Emilie and destroys much of the island. Amicia's group rescues Arnaud before escaping on Sophia's ship, with Victor in pursuit. Victor wounds Amicia and captures Hugo while the rest are forced overboard. On shore, Arnaud sacrifices himself to allow Amicia to kill Victor, but they are too late to prevent Hugo, who believes Amicia to be dead, from giving himself over to the Macula. A cloud blots out the sun, allowing the rats to spread unchecked and destroy Marseille. Amicia and Lucas enter the ruined city and are taken into a phantasmic reality created by the Macula. Here, Hugo's voice tells Amicia that, having now fully merged with the Macula himself, the only way to stop the rats is to kill him. Hugo is killed by Lucas if Amicia refuses to do so.
A year later, Amicia has a home in the mountains, and Lucas is continuing his alchemy studies elsewhere. She prepares to travel with Sophia to find the next Macula carrier and protector so that she can help guide them. Before she leaves, she pays her respects to Hugo at his grave.
In a post-credits scene set in the modern day, a child is on a ventilator with signs of the Macula on their skin.