Bone

Bone follows the eponymous Bone cousins, who appear as white-skinned bone shaped cartoon humanoids: everyman Fone Bone, wealthy and self-serving Phoncible P. "Phoney" Bone, and simpleminded Smiley Bone. When Phoney mounts an ill-fated campaign for mayor, he is forced out of their hometown of Boneville, with Smiley and a reluctant Fone Bone following him. After the cousins find themselves in a desert, Smiley finds a hand-drawn map that they use to navigate their way across the fantasy landscape. The cousins are separated by a swarm of locusts and individually end up in a large valley, a journey made more difficult by the pursuing Rat Creatures.
Eventually, they reunite at the Barrelhaven tavern, where they are taken in by a girl named Thorn and her grandmother, "Gran'ma Ben". Fone Bone instantly develops a crush on Thorn and repeatedly attempts to express his love through poetry. As they stay longer in the Valley, they learn that it is under threat from the Rat Creatures, led by Kingdok, and the mysterious ”Hooded One" who serves an ancient evil known as the Lord of the Locusts. As Thorn learns that she and Gran'ma Ben are the only survivors of the Valley's royal family, the Bones are gradually drawn into the events around them, compelling them on a hero's journey to help free the Valley.